Journal article
Calmodulin Stimulation of Plasmalemmal Ca2+-Pump of Canine Aortic Smooth Muscle
Abstract
Plasma-membrane-enriched fractions of canine aortic smooth muscle possess an ATP-supported Ca2+ accumulation which has an absolute requirement for Mg2+ and a high affinity for Ca2+ (Km approximately 0.5 microM). The rate of ATP-supported Ca2+ transport is not affected by several calmodulin antagonists, but is stimulated by exogenously added calmodulin. The maximal effect of calmodulin on the rate of ATP-dependent Ca2+ transport (at 5.0 microM …
Authors
Kwan CY; Kostka P; Grover AK; Law JS; Daniel EE
Journal
Blood Vessels, Vol. 23, No. 1, pp. 22–33
Publisher
Karger Publishers
Publication Date
1986
DOI
10.1159/000158622
ISSN
0303-6847