Journal article
Mechanism of noncholinergic excitation of canine ileal circular muscle by motilin
Abstract
In the isolated perfused canine ileal segment, exogenous motilin infused for 9 min, at concentrations from 10(-10) M and 10(-8) M, increased circular muscle motility concomitant with inhibiting tonic VIP release, maximum at 10(-8) M. Both effects increased with increasing motilin concentrations. Atropine 10(-7) M pretreatment did not alter these responses. Naloxone 10(-7) M pretreatment eliminated both the increase in motor activity and the …
Authors
Fox-Threlkeld JET; Manaka H; Manaka Y; Cipris S; Woskowska Z; Daniel EE
Journal
Peptides, Vol. 12, No. 5, pp. 1047–1050
Publisher
Elsevier
Publication Date
9 1991
DOI
10.1016/0196-9781(91)90058-w
ISSN
0196-9781