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Covalently closed circles of adenovirus 5 DNA
Journal article

Covalently closed circles of adenovirus 5 DNA

Abstract

The genome of adenoviruses is a double-stranded linear DNA molecule with inverted terminal repeats about 100 base pairs (bp) in length1,2 and a terminal protein covalently linked to the 5′ nucleotide of each strand3,4. Both of these features permit the formation of DNA circles, the inverted repeats allowing the circularization of single-stranded DNA5,6 and the terminal protein the joining of one or more molecules to yield double-stranded …

Authors

Ruben M; Bacchetti S; Graham F

Journal

Nature, Vol. 301, No. 5896, pp. 172–174

Publisher

Springer Nature

Publication Date

January 1983

DOI

10.1038/301172a0

ISSN

0028-0836