Journal article
Programming a topologically constrained DNA nanostructure into a sensor
Abstract
Many rationally engineered DNA nanostructures use mechanically interlocked topologies to connect individual DNA components, and their physical connectivity is achieved through the formation of a strong linking duplex. The existence of such a structural element also poses a significant topological constraint on functions of component rings. Herein, we hypothesize and confirm that DNA catenanes with a strong linking duplex prevent component rings …
Authors
Liu M; Zhang Q; Li Z; Gu J; Brennan JD; Li Y
Journal
Nature Communications, Vol. 7, No. 1,
Publisher
Springer Nature
DOI
10.1038/ncomms12074
ISSN
2041-1723