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Secretory leukocyte proteinase inhibitor is a...
Journal article

Secretory leukocyte proteinase inhibitor is a major leukocyte elastase inhibitor in human neutrophils

Abstract

Secretory leukocyte proteinase inhibitor (SLPI) is the main neutrophil elastase (HLE) inhibitor found in the upper airways during pulmonary inflammation. It has been shown to be synthesized and secreted in vitro by epithelial cells and has been localized in tracheal glands and bronchiolar epithelial cells by immunocytochemistry. In this study, using immunodetection and immunopurification techniques with specific anti-SLPI immunoglobulin G …

Authors

Sallenave J-M; har MS-T; Cox G; Chignard M; Gauldie J

Journal

Journal of Leukocyte Biology, Vol. 61, No. 6, pp. 695–702

Publisher

Oxford University Press (OUP)

Publication Date

June 1, 1997

DOI

10.1002/jlb.61.6.695

ISSN

0741-5400