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Low-Molecular-Weight Heparin versus a Coumarin for...
Journal article

Low-Molecular-Weight Heparin versus a Coumarin for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer

Abstract

BACKGROUND: Patients with cancer have a substantial risk of recurrent thrombosis despite the use of oral anticoagulant therapy. We compared the efficacy of a low-molecular-weight heparin with that of an oral anticoagulant agent in preventing recurrent thrombosis in patients with cancer. METHODS: Patients with cancer who had acute, symptomatic proximal deep-vein thrombosis, pulmonary embolism, or both were randomly assigned to receive …

Authors

Lee AYY; Levine MN; Baker RI; Bowden C; Kakkar AK; Prins M; Rickles FR; Julian JA; Haley S; Kovacs MJ

Journal

The New England Journal of Medicine, Vol. 349, No. 2, pp. 146–153

Publisher

Massachusetts Medical Society

Publication Date

July 10, 2003

DOI

10.1056/nejmoa025313

ISSN

0028-4793