Journal article
Is Enflurane Hepatotoxic?.
Abstract
We evaluated 88 cases of hepatic injury that followed, and were attributed to, enflurane anesthesia. In 30 of the cases, data were insufficient to assess the role of enflurane vs other variables as causal factors. In 43 ("unlikely") patients, factors known to produce hepatic injury were clearly present; in the remaining 15 ("possible"), such factors were not evident. No consistent pathologic change was found in liver specimens from either the …
Authors
Eger EII; Smuckler EA; Ferrell LD; Goldsmith CH; Johnson BH
Journal
Anesthesia & Analgesia, Vol. 65, No. 1,
Publisher
Wolters Kluwer
Publication Date
1 1986
DOI
10.1213/00000539-198601000-00004
ISSN
0003-2999