Journal article
Adenosine and its nucleotides stimulate proliferation of chick astrocytes and human astrocytoma cells
Abstract
Aqueous extracts of the brains of 18-day-old white Leghorn chicken embryos contain several substances that stimulate proliferation of primary cultures of chick brain astrocytes. Most of the mitogens are peptides. Purification of one mitogenic fraction was obtained by centrifugation, passage through Amicon Diaflo membranes of nominal molecular weight cutoffs 30, 1 and 0.5 kDa, ion exchange chromatography and reverse phase high performance liquid …
Authors
Rathbone MP; Middlemiss PJ; Kim J-K; Gysbers JW; DeForge SP; Smith RW; Hughes DW
Journal
Neuroscience Research, Vol. 13, No. 1, pp. 1–17
Publisher
Elsevier
Publication Date
February 1992
DOI
10.1016/0168-0102(92)90030-g
ISSN
0168-0102