Journal article
Does anaesthesia with nitrous oxide affect mortality or cardiovascular morbidity? A systematic review with meta-analysis and trial sequential analysis
Abstract
BACKGROUND: The role of nitrous oxide in modern anaesthetic practice is contentious. One concern is that exposure to nitrous oxide may increase the risk of cardiovascular complications. ENIGMA II is a large randomized clinical trial currently underway which is investigating nitrous oxide and cardiovascular complications. Before the completion of this trial, we performed a systematic review and meta-analysis, using Cochrane methodology, on the …
Authors
Imberger G; Orr A; Thorlund K; Wetterslev J; Myles P; Møller AM
Journal
British Journal of Anaesthesia, Vol. 112, No. 3, pp. 410–426
Publisher
Elsevier
Publication Date
3 2014
DOI
10.1093/bja/aet416
ISSN
0007-0912