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Prevention of Venous Thrombosis With Small,...
Journal article

Prevention of Venous Thrombosis With Small, Subcutaneous Doses of Heparin

Abstract

The effect of low-dose heparin prophylaxis on venous thrombosis and bleeding after major elective surgery was studied in a prospective controlled study of 820 patients. The total incidence of venous thrombosis detected with leg-scanning using fibrinogen labeled with radioactive iodine (125I) was reduced from 16.0% in the control group to 4.2% in treated patients. More important, the incidence of popliteal or femoral vein thrombosis was reduced …

Authors

Gallus AS; Hirsh J; O'Brien SE; McBride JA; Tuttle RJ; Gent M

Journal

JAMA: The Journal of the American Medical Association, Vol. 235, No. 18, pp. 1980–1982

Publisher

American Medical Association (AMA)

Publication Date

May 3, 1976

DOI

10.1001/jama.1976.03260440032018

ISSN

0098-7484