Journal article
Herpes simplex virus 2 causes apoptotic infection in monocytoid cells
Abstract
Increasing evidence indicates that apoptosis can be associated with several viral infections. Here we demonstrate, that infection of monocytoid cells by Herpes simplex virus 2 (HSV-2) resulted, in time- and dose-dependent induction of apoptosis as an exclusive cytopathic effect. The phenomenon was confirmed using four different techniques. Conversely, apoptosis was not observed in the Vero cell line. Virus yield in monocytoid cells was delayed …
Authors
Mastino A; Sciortino MT; Medici MA; Perri D; Ammendolia MG; Grelli S; Amici C; Pernice A; Guglielmino S
Journal
Cell Death & Differentiation, Vol. 4, No. 7, pp. 629–638
Publisher
Springer Nature
Publication Date
10 1997
DOI
10.1038/sj.cdd.4400289
ISSN
1350-9047