Journal article
Accelerated Infusion of Streptokinase for the Treatment of Left-Sided Prosthetic Valve Thrombosis
Abstract
BACKGROUND: No large prospective studies have evaluated the efficacy of fibrinolytic therapy for left-sided prosthetic valve thrombosis, yet it remains the first line of treatment in developing countries.
METHODS AND RESULTS: We performed a randomized controlled trial comparing an accelerated infusion with the conventional infusion of streptokinase in 120 patients with a first episode of left-sided prosthetic valve thrombosis. The primary …
Authors
Karthikeyan G; Math RS; Mathew N; Shankar B; Kalaivani M; Singh S; Bahl VK; Hirsh J; Eikelboom JW
Journal
Circulation, Vol. 120, No. 12, pp. 1108–1114
Publisher
Wolters Kluwer
Publication Date
September 22, 2009
DOI
10.1161/circulationaha.109.876706
ISSN
0009-7322