Journal article
Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials
Abstract
BACKGROUND: Four new oral anticoagulants compare favourably with warfarin for stroke prevention in patients with atrial fibrillation; however, the balance between efficacy and safety in subgroups needs better definition. We aimed to assess the relative benefit of new oral anticoagulants in key subgroups, and the effects on important secondary outcomes.
METHODS: We searched Medline from Jan 1, 2009, to Nov 19, 2013, limiting searches to phase 3, …
Authors
Ruff CT; Giugliano RP; Braunwald E; Hoffman EB; Deenadayalu N; Ezekowitz MD; Camm AJ; Weitz JI; Lewis BS; Parkhomenko A
Journal
The Lancet, Vol. 383, No. 9921, pp. 955–962
Publisher
Elsevier
Publication Date
3 2014
DOI
10.1016/s0140-6736(13)62343-0
ISSN
0140-6736