HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase.
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Overview
status
publication date
- February 2015
has subject area
- 03 Chemical Sciences (FoR)
- 06 Biological Sciences (FoR)
- 11 Medical and Health Sciences (FoR)
- Biochemistry & Molecular Biology (Science Metrix)
published in
- Journal of Biological Chemistry Journal