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Effect of omeprazole on intragastric bacterial...
Journal article

Effect of omeprazole on intragastric bacterial counts, nitrates, nitrites, and N-nitroso compounds.

Abstract

Previous studies have suggested that profound inhibition of gastric acid secretion may increase exposure to potentially carcinogenic N-nitroso compounds. The aim of this study was to find out if the proton pump inhibitor omeprazole (20 mg daily) is associated with increased concentrations of potentially carcinogenic N-nitroso compounds in gastric juice. The volume of gastric contents, number of bacteria, and concentrations of nitrates, …

Authors

Verdu E; Viani F; Armstrong D; Fraser R; Siegrist HH; Pignatelli B; Idström JP; Cederberg C; Blum AL; Fried M

Journal

Gut, Vol. 35, No. 4,

Publisher

BMJ

Publication Date

April 1, 1994

DOI

10.1136/gut.35.4.455

ISSN

0017-5749