Genetic signature of bacterial pathogen adaptation during chronic pulmonary infections Academic Article uri icon

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abstract

  • To establish and maintain chronic infections, many pathogens adapt in response to selective pressures within the host, leaving unique genetic signatures. A new study uses whole-genome and population sequencing approaches to identify evidence of adaptive evolution in Burkholderia dolosa genomes isolated from chronic infections in patients with cystic fibrosis.

publication date

  • January 2014