Journal article
Pre- and Postnatal Nutritional Histories Influence Reproductive Maturation and Ovarian Function in the Rat
Abstract
BACKGROUND: While prepubertal nutritional influences appear to play a role in sexual maturation, there is a need to clarify the potential contributions of maternal and childhood influences in setting the tempo of reproductive maturation. In the present study we employed an established model of nutritional programming to evaluate the relative influences of prenatal and postnatal nutrition on growth and ovarian function in female offspring.
Authors
Sloboda DM; Howie GJ; Pleasants A; Gluckman PD; Vickers MH
Journal
PLOS ONE, Vol. 4, No. 8,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0006744
ISSN
1932-6203