Journal article
Adverse metabolic phenotype of adolescent girls with non‐alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boys
Abstract
BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) share risk associations of adiposity and insulin resistance. We examined the impact of a PCOS diagnosis on the metabolic phenotype of adolescent girls with NAFLD and compared this to girls without PCOS or NAFLD and to age-matched boys.
METHODS: Community-based adolescents from the Raine Cohort participated in assessments for NAFLD (572 girls and …
Authors
Ayonrinde OT; Adams LA; Doherty DA; Mori TA; Beilin LJ; Oddy WH; Hickey M; Sloboda DM; Olynyk JK; Hart R
Journal
Journal of Gastroenterology and Hepatology, Vol. 31, No. 5, pp. 980–987
Publisher
Wiley
Publication Date
May 2016
DOI
10.1111/jgh.13241
ISSN
0815-9319
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdiposityAdolescentAge DistributionBiomarkersCase-Control StudiesChi-Square DistributionFemaleHumansInsulin ResistanceLogistic ModelsMaleMultivariate AnalysisNon-alcoholic Fatty Liver DiseaseObesityOdds RatioPhenotypePolycystic Ovary SyndromePrevalenceRisk FactorsSex DistributionSkinfold ThicknessWestern Australia