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Expression, refolding, crystallization and...
Journal article

Expression, refolding, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgE

Abstract

AlgE is an outer membrane protein present in alginate-producing (mucoid) Pseudomonas aeruginosa. AlgE has been overexpressed in insoluble inclusion bodies, purified under denaturing conditions and refolded in a buffer containing decyl beta-D-maltopyranoside. Purified refolded AlgE was detergent-exchanged into n-octyl tetraoxyethylene and diffraction-quality crystals were grown using the hanging-drop vapor-diffusion method. The crystals grew as …

Authors

Whitney JCC; Neculai AM; Ohman DE; Howell PL

Journal

Acta Crystallographica Section F: Structural Biology Communications, Vol. 65, No. 5, pp. 463–466

Publisher

International Union of Crystallography (IUCr)

Publication Date

May 1, 2009

DOI

10.1107/s174430910901094x

ISSN

2053-230X