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Hypothalamic pathology in the neuroleptic...
Journal article

Hypothalamic pathology in the neuroleptic malignant syndrome

Abstract

The pathogenesis of the neuroleptic malignant syndrome is currently unclear, and no specific morphological abnormalities in the CNS of victims of neuroleptic malignant syndrome have been described. The authors report a case of neuroleptic malignant syndrome with recent foci of necrosis in the anterior and lateral hypothalamic nuclei. They discuss the role of tricyclic antidepressants, monoamine oxidase inhibitors, and neuroleptics in the …

Authors

Horn E; Lach B; Lapierre Y; Hrdina P

Journal

American Journal of Psychiatry, Vol. 145, No. 5, pp. 617–620

Publisher

American Psychiatric Association Publishing

Publication Date

May 1, 1988

DOI

10.1176/ajp.145.5.617

ISSN

0002-953X