Beyond current guidelines: reduction in minimum administered radiopharmaceutical activity with preserved diagnostic image quality in pediatric hepatobiliary scintigraphy

PurposeTo determine if the minimum administered radiopharmaceutical activity for hepatobiliary scintigraphy can be reduced while preserving diagnostic image quality using enhanced planar processing (EPP).MethodsA total of 40 infants between 10 and 270 days old (body mass 2.2 – 6.5 kg) had hepatobiliary scintigraphy during the period 2004 – 2010 following the intravenous administration of either 99mTc-mebrofenin (18 patients) or 99mTc-disofenin …