Journal article
On the origin of rhythmic contractile activity of the esophagus in early achalasia, a clinical case study
Abstract
A patient with early achalasia presented spontaneous strong rhythmic non-propulsive contractions at ~7/min, independent of swallows. Our aim was to evaluate characteristics of the rhythmic contractions, provide data on the structure of pacemaker cells in the esophagus and discuss a potential role for interstitial cells of Cajal (ICC) in the origin of rhythmicity. We hypothesize that intramuscular ICC (ICC-IM) are the primary pacemaker cells. …
Authors
Chen J-H; Wang X-Y; Liu LWC; Yu W; Yu Y; Zhao L; Huizinga JD
Journal
Frontiers in Neuroscience, Vol. 7, ,
Publisher
Frontiers
DOI
10.3389/fnins.2013.00077
ISSN
1662-4548