Multiple hypoechoic hepatic lesions in a patient with Gaucher disease. Academic Article uri icon

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  • The most common symptoms of Gaucher disease include hepatosplenomegaly and anemia and thrombocytopenia due to hypersplenism. We describe the case of a patient with Gaucher disease who had cachexia, massive hepatomegaly, and multiple focal hepatic lesions. The clinical and radiologic findings suggested malignancy. A biopsy specimen was taken from a hepatic lesion and revealed infiltration by Gaucher cells. We discuss our findings in light of the putative increased incidence of hematologic malignancies in patients with Gaucher disease.


  • Patlas, Michael
  • Hadas-Halpern, Irith
  • Reinus, Constantin
  • Zimran, Ari
  • Elstein, Deborah

publication date

  • 2002