Duchenne Muscular Dystrophy Manifesting Carriers

To the Editor. —The article by Barkhaus and Gilchrist in the June 1989 issue of the Archives1 makes the appropriate point that Duchenne dystrophy in manifesting female carriers may be difficult to distinguish clinically from sporadic autosomal recessive limb-girdle muscular dystrophy. Limb-girdle muscular dystrophy is a heterogeneous syndrome, however, and autosomal dominant forms should also be considered in the differential diagnosis of …