Anticoagulation in venous Thrombosis Journal Articles

abstract

• Major studies addressing various aspects of the treatment of deep vein thrombosis are reviewed. It has lately been demonstrated that heparin should be dosed according to body weight and is preferably given as subcutaneous injections twice daily. Alternatively, low-molecular-weight heparins may be given in a fixed dose once daily, which does not require monitoring. Oral anticoagulation should be started concomitantly with heparin and targeted at an international normalized ratio of 2.0-3.0. This treatment should continue for a longer duration than previously accepted, in many cases for 6 months. For patients with contraindications to oral anticoagulation, secondary prophylaxis with a low-molecular-weight heparin is also effective and safe.

authors

• Schulman, Sam

status

• published 

publication date

• November 1996

has subject area

• 1117 Public Health and Health Services (FoR)
• Administration, Oral (MeSH)
• Anticoagulants (MeSH)
• Female (MeSH)
• General & Internal Medicine (Science Metrix)
• Heparin (MeSH)
• Humans (MeSH)
• Infusions, Intravenous (MeSH)
• Injections, Subcutaneous (MeSH)
• Pregnancy (MeSH)
• Pregnancy Complications, Hematologic (MeSH)
• Randomized Controlled Trials as Topic (MeSH)
• Thrombophlebitis (MeSH)
• Treatment Outcome (MeSH)

published in

• Journal of the Royal Society of Medicine  Journal

keywords

• Administration, Oral
• Anticoagulants
• Female
• Heparin
• Humans
• Infusions, Intravenous
• Injections, Subcutaneous
• Pregnancy
• Pregnancy Complications, Hematologic
• Randomized Controlled Trials as Topic
• Thrombophlebitis
• Treatment Outcome

Digital Object Identifier (DOI)

• 10.1177/014107689608901108

start page

• 624

end page

• 630

volume

• 89

issue

• 11