Journal article
Driving Pressure and Survival in the Acute Respiratory Distress Syndrome
Abstract
BACKGROUND: Mechanical-ventilation strategies that use lower end-inspiratory (plateau) airway pressures, lower tidal volumes (VT), and higher positive end-expiratory pressures (PEEPs) can improve survival in patients with the acute respiratory distress syndrome (ARDS), but the relative importance of each of these components is uncertain. Because respiratory-system compliance (CRS) is strongly related to the volume of aerated remaining …
Authors
Amato MBP; Meade MO; Slutsky AS; Brochard L; Costa ELV; Schoenfeld DA; Stewart TE; Briel M; Talmor D; Mercat A
Journal
The New England Journal of Medicine, Vol. 372, No. 8, pp. 747–755
Publisher
Massachusetts Medical Society
Publication Date
February 19, 2015
DOI
10.1056/nejmsa1410639
ISSN
0028-4793