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High mobility group protein HMGA1 expression in...
Journal article

High mobility group protein HMGA1 expression in breast cancer reveals a positive correlation with tumour grade.

Abstract

Members of the HMGA protein (high mobility group protein A) family act as master switches of the chromatin structure by bending DNA and thus modulating the formation of transcription factor complexes of a number of target genes. Accordingly, HMGA proteins have been shown to be associated with the development and/or progression of a variety of benign and malignant tumours. Nevertheless, the HMGA1 expression studies published so far have not …

Authors

Flohr AM; Rogalla P; Bonk U; Puettmann B; Buerger H; Gohla G; Packeisen J; Wosniok W; Loeschke S; Bullerdiek J

Journal

Histology and histopathology, Vol. 18, No. 4, pp. 999–1004

Publication Date

October 2003

DOI

10.14670/hh-18.999

ISSN

0213-3911