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BEST1-related autosomal dominant...
Journal article

BEST1-related autosomal dominant vitreoretinochoroidopathy: a degenerative disease with a range of developmental ocular anomalies

Abstract

PurposeTo describe the spectrum of phenotypic characteristics of BEST1-related autosomal dominant vitreoretinochoroidopathy (ADVIRC) in a family with p.V86M mutation.MethodsA retrospective review of the clinical, psychophysical, and electrophysiological phenotypes of six subjects with ADVIRC. Five family members were sequenced for mutations in the BEST1gene.ResultsA heterozygous change, p.V86M (c.256G>A), was identified in the BEST1gene in the …

Authors

Vincent A; McAlister C; VandenHoven C; Héon E

Journal

Eye, Vol. 25, No. 1, pp. 113–118

Publisher

Springer Nature

Publication Date

1 2011

DOI

10.1038/eye.2010.165

ISSN

0950-222X