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Noninvasive Measurement of Exhaled Nitric Oxide in...
Journal article

Noninvasive Measurement of Exhaled Nitric Oxide in a Spontaneously Breathing Mouse

Abstract

Nitric oxide (NO) has been detected in the exhaled gas of animals and humans. In previous work, investigators have used anesthetized, mechanically ventilated animals to obtain exhaled NO (E(NO)) measurements, which has unclear effects on the levels of E(NO) and does not allow for repeated analysis of E(NO). We sought to measure E(NO) from a single, spontaneously breathing mouse. The mouse was placed in a small Plexiglas chamber and allowed to …

Authors

WEICKER S; KARACHI TA; SCOTT JA; McCORMACK DG; MEHTA S

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 163, No. 5, pp. 1113–1116

Publisher

American Thoracic Society

Publication Date

April 1, 2001

DOI

10.1164/ajrccm.163.5.2007025

ISSN

1073-449X