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Triplets with neonatal alloimmune thrombocytopenia...
Journal article

Triplets with neonatal alloimmune thrombocytopenia due to antibodies against human platelet antigen 1a

Abstract

BACKGROUND: Neonatal alloimmune thrombocytopenia (NAIT) has been reported only rarely in twins and not at all, to our knowledge, in triplets. CASE REPORT: Nonidentical triplets were born with severe thrombocytopenia. Nadir platelet (PLT) counts were 17 × 109 , 12 × 109 , and 10 × 109 /L. NAIT was confirmed by an incompatibility for human PLT antigen (HPA)-1a and the presence of maternal anti-HPA-1a. The maternal genotype was HPA-1bb and the …

Authors

Solh Z; Breakey V; Murthy P; Smith JW; Arnold DM

Journal

Transfusion, Vol. 56, No. 5, pp. 1166–1170

Publisher

Wiley

Publication Date

May 2016

DOI

10.1111/trf.13494

ISSN

0041-1132