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Treatment of Aspergillus fumigatus in Patients...
Journal article

Treatment of Aspergillus fumigatus in Patients with Cystic Fibrosis: A Randomized, Placebo-Controlled Pilot Study

Abstract

BACKGROUND: Many patients with cystic fibrosis develop persistent airway infection/colonization with Aspergillus fumigatus, however the impact of A. fumigatus on clinical outcomes remains unclear. The objective of this study was to determine whether treatment directed against Aspergillus fumigatus improves pulmonary function and clinical outcomes in patients with cystic fibrosis (CF). METHODS: We performed a double-blind randomized …

Authors

Aaron SD; Vandemheen KL; Freitag A; Pedder L; Cameron W; Lavoie A; Paterson N; Wilcox P; Rabin H; Tullis E

Journal

PLOS ONE, Vol. 7, No. 4,

Publisher

Public Library of Science (PLoS)

Publication Date

2012

DOI

10.1371/journal.pone.0036077

ISSN

1932-6203