Journal article
First trimester biochemical screening for Down syndrome: free beta hCG versus intact hCG
Abstract
To compare free beta hCG versus intact hCG in first trimester Down syndrome screening we analysed 63 cases of Down syndrome and 400 unaffected control pregnancies between 10 and 13 weeks' gestation. The Down syndrome median multiple of the median (MoM) was significantly higher (p=0.001) for free beta hCG (1.89 MoM) than for intact hCG (1.37 MoM). Although distributions for free beta hCG (unaffected, 0.2157; DS, 0.2322) are wider than for intact …
Authors
Hallahan T; Krantz D; Orlandi F; Rossi C; Curcio P; Macri S; Larsen J; Buchanan P; Macri J
Journal
Prenatal Diagnosis, Vol. 20, No. 10, pp. 785–789
Publisher
Wiley
Publication Date
October 2000
DOI
10.1002/1097-0223(200010)20:10<785::aid-pd892>3.0.co;2-6
ISSN
0197-3851