Blinded interpretation of study results can feasibly and effectively diminish interpretation bias

OBJECTIVE: Controversial and misleading interpretation of data from randomized trials is common. How to avoid misleading interpretation has received little attention. Herein, we describe two applications of an approach that involves blinded interpretation of the results by study investigators. STUDY DESIGN AND SETTINGS: The approach involves developing two interpretations of the results on the basis of a blinded review of the primary outcome …