Moisturizers and Ceramide-containing Moisturizers May Offer Concomitant Therapy with Benefits. Academic Article uri icon

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  • INTRODUCTION: Ceramide-containing moisturizers may offer benefits as an adjunct to acne treatment. METHODS: An expert panel of 11 Canadian dermatologists, including an international clinical scientist, used the following modified Delphi process: 1) A systematic literature review for acne treatment, dry skin, irritation, depletion of ceramides in acne, and benefits of moisturizers and ceramide-containing moisturizers was conducted; 2) panel members gave their opinion on the resulting statements, taking into account their treatment practices; 3) a panel meeting was held during the 2011 Canadian Dermatology Update to determine final statements; 4) the panel reviewed the final document. RESULTS: The panel reached the following consensus (11/11): 1) A very important reason for nonadherence to acne treatment is dry skin and irritation; 2) skin barrier dysfunction may contribute to acne; 3) dry skin and irritation commonly results from topical acne treatment; 4) dry skin and irritation commonly results from systemic retinoid therapy; 5) moisturizers can improve dryness and irritation resulting from acne treatment; 6) ceramide-containing moisturizers may enhance adherence and complement existing acne therapies; 7) adjunctive therapy with moisturizers should be considered in acne-treated patients. CONCLUSION: The panel proposes that adjunctive therapy with moisturizers, particularly ceramide-containing moisturizers, should be considered in acne-treated patients.


  • Lynde, Chuck W
  • Andriessen, Anneke
  • Barankin, Benjamin
  • Gannes, Gillian De
  • Gulliver, Wayne
  • Haber, Richard
  • McCuaig, Catherine
  • Rajan, Poonam
  • Skotnicki, Sandra P
  • Thomas, Richard
  • Toole, Jack
  • Vender, Ronald

publication date

  • March 2014