Journal article
Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity
Abstract
CONTEXT: Very preterm infants are prone to apnea and have an increased risk of death or disability. Caffeine therapy for apnea of prematurity reduces the rates of cerebral palsy and cognitive delay at 18 months of age.
OBJECTIVE: To determine whether neonatal caffeine therapy has lasting benefits or newly apparent risks at early school age.
Authors
Schmidt B; Anderson PJ; Doyle LW; Dewey D; Grunau RE; Asztalos EV; Davis PG; Tin W; Moddemann D; Solimano A
Journal
JAMA, Vol. 307, No. 3, pp. 275–282
Publisher
American Medical Association (AMA)
Publication Date
January 18, 2012
DOI
10.1001/jama.2011.2024
ISSN
0098-7484
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
ApneaBlindnessCaffeineCentral Nervous System StimulantsCerebral PalsyChild DevelopmentChild, PreschoolCognition DisordersDeafnessDevelopmental DisabilitiesFemaleFollow-Up StudiesHumansIncidenceInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightMaleOdds RatioSurvival AnalysisTreatment Outcome