Journal article
Effects of Targeting Higher vs Lower Arterial Oxygen Saturations on Death or Disability in Extremely Preterm Infants: A Randomized Clinical Trial
Abstract
IMPORTANCE: The goal of oxygen therapy is to deliver sufficient oxygen to the tissues while minimizing oxygen toxicity and oxidative stress. It remains uncertain what values of arterial oxygen saturations achieve this balance in preterm infants.
OBJECTIVE: To compare the effects of targeting lower or higher arterial oxygen saturations on the rate of death or disability in extremely preterm infants.
Authors
Schmidt B; Whyte RK; Asztalos EV; Moddemann D; Poets C; Rabi Y; Solimano A; Roberts RS; Group FTCOT
Journal
JAMA: The Journal of the American Medical Association, Vol. 309, No. 20, pp. 2111–2120
Publisher
American Medical Association (AMA)
Publication Date
May 22, 2013
DOI
10.1001/jama.2013.5555
ISSN
0098-7484
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultBlindnessCognition DisordersChildren with DisabilitiesDouble-Blind MethodFemaleGestational AgeHearing LossHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightLanguage Development DisordersMaleMortalityOdds RatioOxygenOxygen Inhalation TherapyRetinopathy of PrematurityTreatment Outcome