Scholarly Works

Inhibition of urease activity but not growth of...

Journal article

Inhibition of urease activity but not growth of Helicobacter pylori by acetohydroxamic acid.

Abstract

The in vitro effects of acetohydroxamic acid (AHA), a potent urease inhibitor, were studied to determine the effect on the urease activity and growth of 38 strains of Helicobacter pylori. AHA in concentrations of 50-1000 mg/l had a noticeably reversible inhibitory effect on the urease activity of the organism but no effect on growth.

Authors

Goldie J; van Zanten SJV; Jalali S; Richardson H; Hunt RH

Journal

Journal of Clinical Pathology, Vol. 44, No. 8,

Publisher

BMJ

Publication Date

January 1, 1991

DOI

10.1136/jcp.44.8.695

ISSN

0021-9746

Associated Experts

Richard Hunt

Professor Emeritus, FHSMED

Subash Jalali

Assistant Clinical Professor, FHSMED

Labels

Fields of Research (FoR)

3214 Pharmacology and Pharmaceutical Sciences 32 Biomedical and Clinical Sciences 3202 Clinical sciences 3211 Oncology and carcinogenesis

Medical Subject Headings (MeSH)

Dose-Response Relationship, Drug Helicobacter pylori Hydroxamic Acids Urease

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