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Comparing influenza vaccine efficacy against...
Journal article

Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

Abstract

BackgroundInfluenza vaccines are most effective when the antigens in the vaccine match those of circulating strains. However, antigens contained in the vaccines do not always match circulating strains. In the present work we aimed to examine the vaccine efficacy (VE) afforded by influenza vaccines when they are not well matched to circulating strains.MethodsWe identified randomized clinical trials (RCTs) through MEDLINE, EMBASE, the Cochrane …

Authors

Tricco AC; Chit A; Soobiah C; Hallett D; Meier G; Chen MH; Tashkandi M; Bauch CT; Loeb M

Journal

BMC Medicine, Vol. 11, No. 1,

Publisher

Springer Nature

Publication Date

12 2013

DOI

10.1186/1741-7015-11-153

ISSN

1741-7015