Journal article
Interaction Between Sympathetic Nervous System and Adrenal Medulla in the Control of Cardiovascular Changes in Hypertension
Abstract
The role of the sympathetic nervous system and adrenal medulla in the development of cardiovascular changes and hypertension was studied in spontaneously hypertensive rats (SHRs), and the results compared with age-matched normotensive Wistar-Kyoto (WKY) rats. Sympathectomy was initiated in newborn rats through daily injection with antiserum to nerve growth factor for 1 week, followed by daily injection with guanethidine for 3 weeks. Removal of …
Authors
Lee RMKW; Borkowski KR; Leenen FHH; Tsoporis J; Coughlin M
Journal
Journal of Cardiovascular Pharmacology, Vol. 17, No. Supplement 2, pp. s114–s116
Publisher
Wolters Kluwer
Publication Date
1991
DOI
10.1097/00005344-199117002-00025
ISSN
0160-2446