Journal article
Predicting 2-Year Survival for Radiation Regimens in Advanced Non-small Cell Lung Cancer
Abstract
AIMS: Total dose, dose per fraction, number of fractions and treatment time are important determinants of the biological effect of a radiation regimen. Several randomised clinical trials (RCTs) have tested a variety of dosing regimens in advanced unresected non-small cell lung cancer, but survival remains poor. This work used past RCT data to develop and validate a predictive model that could help in designing new radiation regimens for …
Authors
Sharieff W; Okawara G; Tsakiridis T; Wright J
Journal
Clinical Oncology, Vol. 25, No. 12, pp. 697–705
Publisher
Elsevier
Publication Date
December 2013
DOI
10.1016/j.clon.2013.07.011
ISSN
0936-6555
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Carcinoma, Non-Small-Cell LungDose Fractionation, RadiationDose-Response Relationship, DrugFemaleHumansLung NeoplasmsMaleModels, BiologicalRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRandomized Controlled Trials as TopicReproducibility of ResultsRisk FactorsSurvival RateTreatment Outcome