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Diclofenac delays healing of gastroduodenal...
Journal article

Diclofenac delays healing of gastroduodenal mucosal lesions

Abstract

The effects of the water-soluble and delayed-release formulations of a nonsteroidal antiinflammatory drug, diclofenac, on the healing of gastroduodenal mucosal lesions were compared in a double-blind, double cross-over, placebo-controlled endoscopic study conducted in 14 healthy volunteers. Severe endoscopic lesions (petechiae, erosions, ulcers, and esophageal candidiasis) were found only in the group taking the soluble formulation of …

Authors

Stadler P; Armstrong D; Margalith D; Saraga E; Stolte M; Lualdi P; Mautone G; Blum AL

Journal

Digestive Diseases and Sciences, Vol. 36, No. 5, pp. 594–600

Publisher

Springer Nature

Publication Date

May 1991

DOI

10.1007/bf01297025

ISSN

0163-2116