Journal article
Systematic Review: Sequential Rescue Therapy in Severe Ulcerative Colitis: Do the Benefits Outweigh the Risks?
Abstract
BACKGROUND: The options for medical management of acute severe steroid-refractory ulcerative colitis (UC) are limited. Recent guidelines recommend against use of sequential rescue therapy in the setting of failed medical management with initial salvage therapy. A systematic review was conducted to assess outcomes of sequential rescue therapy with infliximab (IFX) and calcineurin inhibitors like cyclosporine (CsA) or tacrolimus (Tac) in patients …
Authors
Narula N; Fine M; Colombel J-F; Marshall JK; Reinisch W
Journal
Inflammatory Bowel Diseases, Vol. 21, No. 7, pp. 1683–1694
Publisher
Oxford University Press (OUP)
Publication Date
7 2015
DOI
10.1097/mib.0000000000000350
ISSN
1078-0998