Journal article
B Cell Helper Assays
Abstract
Activation, proliferation and differentiation of naïve B lymphocytes into memory B cells and plasma cells requires engagement of the B cell receptor (BCR) coupled to T-cell help (1, 2). T cells deliver help in cognate fashion when they are activated upon recognition of specific MHC–peptide complexes presented by B cells. T cells can also deliver help in a non-cognate or bystander fashion, when they do not find specific MHC–peptide complexes on …
Authors
Abrignani S; Tonti E; Casorati G; Dellabona P
Journal
Methods in Molecular Biology, Vol. 514, , pp. 15–26
Publisher
Springer Nature
Publication Date
2009
DOI
10.1007/978-1-60327-527-9_2
ISSN
1064-3745