Listeria monocytogenes meningitis in an immunocompromised patient. Academic Article uri icon

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  • This report describes a case of meningitis caused by Listeria monocytogenes in a stem cell transplant recipient on immunosuppressive therapy for cutaneous chronic graft-versus host disease. A 59-year-old woman had undergone allogeneic stem cell transplantation (from a matched unrelated donor) 13 months previously for chronic lymphocytic leukemia. She was on regular hematologic follow-up. Though her previous malignancy has been in remission, she was immunosuppressed due to the pharmacological treatment. We describe a meningitis caused by a typical food-borne pathogen, dangerous in patients with impaired cell-mediated immunity. Moreover the bacterium had a multidrug resistance, a rare characteristic in clinical listeriosis. Rapid diagnosis and treatment are key factors in these cases. We chose ampicillin and rifampicin that allowed a complete resolution of the clinical manifestations.


  • Barocci, Simone
  • Mancini, Alessio
  • Canovari, Benedetta
  • Petrelli, Enzo
  • Sbriscia-Fioretti, Emanuela
  • Licci, Alberto
  • D'Addesa, Simona
  • Petrini, Giancarlo
  • Giacomini, Mita
  • Renzi, Antonella
  • Migali, Antonio
  • Briscolini, Sara

publication date

  • January 2015