Journal article
Pharmacological preconditioning in rabbit myocardium is blocked by chloride channel inhibition
Abstract
OBJECTIVES: We have recently proposed that chloride (Cl(-)) channels contribute to ischemic preconditioning (IPC) in the myocardium. To further evaluate this hypothesis, we investigated the role of Cl(-) channels in pharmacological preconditioning.
METHODS: Isolated rabbit cardiomyocytes and isolated buffer-perfused rabbit hearts were initially preconditioned with a 10 min exposure to either an adenosine receptor agonist …
Authors
Batthish M; Diaz RJ; Zeng H-P; Backx PH; Wilson GJ
Journal
Cardiovascular Research, Vol. 55, No. 3, pp. 660–671
Publisher
Oxford University Press (OUP)
Publication Date
August 15, 2002
DOI
10.1016/s0008-6363(02)00454-6
ISSN
0008-6363