Journal article
Acetylcholine activates non‐selective cation and chloride conductances in canine and guinea‐pig tracheal myocytes.
Abstract
1. Membrane currents activated by acetylcholine (ACh) were investigated in isolated canine and guinea-pig tracheal myocytes using the nystatin perforated patch configuration of whole-cell recording. ACh caused depolarization accompanied by a membrane conductance increase. 2. When cells were held under voltage clamp (holding potential, Vh = -60 mV), ACh elicited inward current (IACh) of up to 3900 pA, with a reversal potential (Erev) of …
Authors
Janssen LJ; Sims SM
Journal
The Journal of Physiology, Vol. 453, No. 1, pp. 197–218
Publisher
Wiley
Publication Date
7 1992
DOI
10.1113/jphysiol.1992.sp019224
ISSN
0022-3751