There has been a gradual increase in the incidence of non-
Candida albicans-related nosocomial infections. Candida glabrataurinary tract infections have increased in frequency, and treating these infections can be difficult because the organism may be resistant to fluconazole. A newer antifungal agent, micafungin, which belongs in the class of echinocandins, provides an alternative and effective therapy against C glabrata. The present report describes three cases of C glabrata-associated urinary tract infections successfully treated with micafungin. To the authors’ knowledge, this is the first report of successful treatment of C glabrataand azole-resistant C albicans-associated urinary tract infection with an echinocandin.