This book presents emerging themes and future directions in the interdisciplinary field of critical data studies, loosely themed around the notion of shifting response-abilities in a datafied world. In each chapter an interdisciplinary group of scholars discuss a specific theme in a dialogic format. The themes range from questions around data power and the configuring of data subjects to the intersection of technology and the environment. The book is an invaluable dialogue between disciplines that introduces readers to cutting edge arguments within the field. It will be a key resource for scholars and students who require a guide to this rapidly evolving area of research. Available open access digitally under CC-BY-NC-ND licence. This book presents emerging themes and future directions in the interdisciplinary field of critical data studies, loosely themed around the notion of shifting response-abilities in a datafied world. In each chapter an interdisciplinary group of scholars discuss a specific theme, ranging from questions around data power and the configuring of data subjects to the intersection of technology and the environment. The book is an invaluable dialogue between disciplines that introduces readers to cutting edge arguments within the field. It will be a key resource for scholars and students who require a guide to this rapidly evolving area of research. Available open access digitally under CC-BY-NC-ND licence. Written in an engaging dialogue format, this book introduces readers to emerging themes and future directions in the interdisciplinary field of data studies. It will be a key resource for scholars and students who require a cutting-edge guide to this rapidly evolving area of research. Datafied systems require data subjects, but how these subjects are configured is often made invisible. This chapter explores the configuration of individuals as data subjects within datafied systems, highlighting the importance of the historical, contextual, social, and power dynamics that shape and determine datafication processes. The chapter discussions question the assumption of data objectivity, emphasizing the impact of data collection, conceptualization, and design choices on the creation of data subjects. Specific areas of datafication are examined, including power dynamics in self-tracking practices, the configuration of older adults and disabled experiences as data subjects, and the definition of data subjects in autonomous vehicles. These collectively reveal how datafication practices are informed by the interplay of data, society, stereotypes, and the self. In examining the implications of datafication and its impact on both individuals and communities, this chapter highlights the multidimensional nature of datafication and the need for transdisciplinary approaches to comprehend the power dynamics, agency, and historical contexts in configuring data subjects. The authors show how critical explorations of the intricate interplay between data subjects, data experts, and data-driven algorithms can help envision alternative configurations for more comprehensive, inclusive, and responsive data and datafication practices.