Microdysgenesis: Historical roots of an important concept in epilepsy

Microdysgenesis (MD) is a term used to refer to subtle brain dysplasia based on structural tissue characteristics seen exclusively under the microscope. Although MD is often referred to within the field of modern epileptology, the term and its implications have actually evolved over a long period in neurology, starting in the late 19th century. This article undertakes a careful evaluation of original publications in the epilepsy literature and …