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Establishing an ex vivo porcine skin model to...
Preprint

Establishing an ex vivo porcine skin model to investigate the effects of broad spectrum antiseptic on viable skin microbial communities

Abstract

Incomplete antiseptic efficacy against potentially pathogenic microbial taxa places some patients at disproportionate risk for developing a surgical site infection. Laboratory models capable of interrogating the effects of antiseptics on the skin and its complex microbial communities are desperately needed to improve and better tailor antiseptic formulations. This work aims to establish an ex vivo porcine skin model to explore the impact of …

Authors

Townsend EC; Xu K; De La Cruz K; Huang L; Sandstrom S; Meudt JJ; Shanmuganayagam D; Huttenlocher A; Gibson ALF; Kalan LR

DOI

10.1101/2025.04.03.647100

Preprint server

bioRxiv